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Because of its involvement in HIV entry, the chemokine receptor CXCR4 is an attractive target for antiretroviral drugs. Despite the large number of CXCR4 inhibitors studied, the 3D pharmacophore for binding to CXCR4 remains elusive, mainly as a result of conformational flexibility inherent in the identified ligands. In the present study, an exhaustive systematic exploration of the conformationa...
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. http://dx.doi.org/10.5045/kjh.2011.46.4.209 The Korean Journal of Hematology Volume 46ᆞNumbe...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 2014
ISSN: 1087-0571,1552-454X
DOI: 10.1177/1087057114526283